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KMID : 1164220130250020181
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Journal of Korean Society for Radiotherapeutic Technology
2013 Volume.25 No. 2 p.181 ~ p.186
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Dose Evaluation of TPS according to Treatment Sites in IMRT
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Kim Jin-Man
Kim Jong-Sik
Hong Chae-Seon
Park Ju-Young
Park Su-Yeon
Ju Sang-Gyu
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Abstract
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Purpose: This study executed therapy plans on prostate cancer (homogeneous density area) and lung cancer
(non-homogeneous density area) using radiation treatment planning systems such as Pinnacle3 (version 9.2,
Philips Medical Systems, USA) and Eclipse (version 10.0, Varian Medical Systems, USA) in order to quantify the
difference between dose calculation according to density in IMRT.
Materials and Methods: The subjects were prostate cancer patients (n=5) and lung cancer patients (n=5) who
had therapies in our hospital. Identical constraints and optimization process according to the Protocol were
administered on the subjects. For the therapy plan of prostate cancer patients, 10 MV and 7Beam were used and
2.5 Gy was prescribed in 28 fx to make 70 Gy in total. For lung cancer patients, 6 MV and 6Beam were used and
2 Gy was prescribed in 33 fx to make 66 Gy in total. Through two therapy planning systems, maximum dose,
average dose, and minimum dose of OAR (Organ at Risk) of CTV, PTV and around tumor were investigated.
Results: In prostate cancer, both therapy planning systems showed within 2% change of dose of CTV and PTV and
normal organs (Bladder, Both femur and Rectum out) near the tumor satisfied the dose constraints. In lung cancer,
CTV and PTV showed less than 2% changes in dose and normal organs (Esophagus, Spinal cord and Both lungs)
satisfied dose restrictions. However, the minimum dose of Eclipse therapy plan was 1.9% higher in CTV and 3.5%
higher in PTV, and in case of both lungs there was 3.0% difference at V5 Gy.
Conclusion: Each TPS according to the density satisfied dose limits of our hospital proving the clinical accuracy.
It is considered more accurate and precise therapy plan can be made if studies on treatment planning for diverse
parts and the application of such TPS are made.
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KEYWORD
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radiation treatment planning systems, intensity modulation radiation therapy, algorithms, inhomogeneity
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